The Collins-Gideon race was the most expensive in Maine history, with national donors flooding the state with tens of millions of dollars and an onslaught of negative campaign ads. The battle for control of the Senate appeared to be heading out of reach for Democrats.Democrats early Wednesday won a crucial seat in Arizona, with Mark Kelly, a former astronaut, defeating Senator Martha McSally, and former Gov. John Hickenlooper defeated Senator Cory Gardner on Tuesday night in the high-profile fight for Colorado’s Senate seat. Those victories were essential to Democrats’ push to take the Senate majority. – Advertisement – – Advertisement – In Georgia, the Rev. Dr. Raphael G. Warnock, a Democrat, advanced to a runoff election against Senator Kelly Loeffler, the Republican incumbent. The other race in the state, between Jon Ossoff, the Democratic challenger, and Senator David Perdue, a Republican, was too close to call. But Republicans across the country were successful in holding off well-funded challengers in a number of key races. In Montana, Senator Steve Daines defeated Gov. Steve Bullock and in Iowa, Senator Joni Ernst defeated Theresa Greenfield, a businesswoman who had styled herself as a “scrappy farm kid.” Senator Lindsey Graham, a Republican, hung onto his seat in South Carolina, fending off the toughest challenge of his political career from Jaime Harrison, a Black Democrat whose upstart campaign electrified progressives across the country and inspired a record-setting onslaught of campaign cash.Senator John Cornyn, Republican of Texas, also defeated a challenge from M.J. Hegar, a former Air Force pilot who Democrats hoped could have an outside chance of winning in the rapidly changing state. In Kentucky, Senator Mitch McConnell, the majority leader, easily won re-election, defeating Amy McGrath, a Democrat who struggled to gain ground despite an outpouring of financial support from her party’s supporters around the nation. – Advertisement –
Keep your floors cleaner than ever—with minimal effort—when you have the Proscenic M7 Pro LDS intelligent robot vacuum. This cool robot vacuum cleaner has a Vboost feature that automatically increases suction power to the maximum mode when it detects carpet. This smart robot vacuum intelligently travels about and maps your home. As it works, it creates a real-time map of your house to plan the ideal cleaning path. Its 24 sensors locate obstacles and help the machine learn the shape of your house. So it’s like you’re there, adjusting the power depending on what you need to vacuum. Best of all, this smart home gadget offers two-in-one cleaning since it can sweep, mop, or sweep and mop synchronously. It’s a smart vacuum that really does it all. – Advertisement –
– Advertisement – Friday 6th November 5:30pm Prutton predicts: 2-2 (Sky Bet odds) Who is David Prutton tipping for victory in the Sky Bet Championship this weekend? Find out here…The Prutton’s Predictions show!Listen to the all new Prutton’s Predictions show! David Prutton joins Sky Sports’ Simeon Gholam to discuss all his Championship predictions ahead of Gameweek 11. You can listen below, as he reveals who he is backing this weekend.- Advertisement – If you want to get involved then tweet your predictions here and we will dissect the best on the show every Thursday before a round of Championship games!Cardiff vs Bristol City, Friday 6pm – Live on Sky Sports FootballThat was a great win for Cardiff in midweek, and Harry Wilson is really getting up to speed which can only bode well for them.Bristol City’s win was curious in midweek as they had not won in five before that and were well beaten by Norwich in midweek. It showed great resolve and this feels like a score draw to me.- Advertisement – Birmingham vs Bournemouth, Saturday 3pmBoth of these sides need a reaction. Birmingham should have beaten Wycombe in midweek, especially after taking the lead, and will be so disappointed to have seen their mini run of wins come to an end.Bournemouth suffered their first defeat of the season at Sheffield Wednesday, but they have the quality to bounce back here. Away win.Prutton predicts: 0-1 (Sky Bet odds)Brentford vs Middlesbrough, Saturday 3pm Kick off 6:00pm Kick off 12:30pm Prutton predicts: 1-2 (Sky Bet odds) Reading vs Stoke, Saturday 12.30pm – Live on Sky Sports FootballIs it surprising Reading lost at home to Preston? They are so good away from home, and it is still too early to worry about the Royals suffering a real dip.Stoke will not be quite sure how they lost at Watford in midweek, and Michael O’Neill will be keen for his side to bounce back as quickly as possible. I think they will do just that.- Advertisement – We often focus on Brentford’s attacking talent and probably ignore at times how good they were defensively last season. There is no doubt they need to tighten up at the back.Middlesbrough and goals do not really go hand in hand this season, but I would like to think there will be goals in this one. I will back Brentford to edge it.Prutton predicts: 2-1 (Sky Bet odds)Norwich vs Swansea, Saturday 3pmIt’s nicely set up this one. Norwich were excellent at Bristol City last Saturday and should have seen off Millwall in midweek.Maybe Swansea are still operating a little under the radar but if they keep in that part of the table that will not last long. I feel like this will be a draw.Prutton predicts: 1-1 (Sky Bet odds)Sheffield Wednesday vs Millwall, Saturday 3pm What a great week for Sheffield Wednesday. A big win against Bournemouth and then to see their points deduction halved. They could be out of the bottom three by Saturday night if things go their way.Are Millwall dark horses for the top six this season? They are going about their business well enough and will be glad to have Gary Rowett back in the dugout. That being said, I think the positivity shrouding Wednesday will fire them to victory.Prutton predicts: 1-0 (Sky Bet odds)Prutton’s other predictions (All Saturday 3pm kick-off/Saturday 3pm kick-off unless stated)Blackburn vs QPR: 1-1 (Sky Bet odds)Derby vs Barnsley: 1-1 (Sky Bet odds)Huddersfield vs Luton: 0-1 (Sky Bet odds)Nottingham Forest vs Wycombe: 2-1 (Sky Bet odds)Rotherham vs Preston: 0-2 (Sky Bet odds)Watford vs Coventry: 2-2 (Sky Bet odds) Saturday 7th November 12:00pm
As the dust settles from the presidential race, the eyes of the political world have already shifted to Georgia, where two runoff elections set for early January will almost certainly determine which party has control of the Senate.The outcome of the contests, which will play out two weeks before President-elect Joseph R. Biden Jr.’s inauguration, will either swing the majority to Democrats, handing the new president broad power to carry out his policy agenda and push through nominations as he sees fit, or leave Republicans in charge, allowing them to influence his plans.- Advertisement – In the weeks ahead, tens of millions of dollars in campaign cash are expected to pour into the state to fund a marathon of political advertising, while party leaders and interest groups on both sides train their attention on the races.Click here to read more about how it will work. – Advertisement –
Valdis Dombrovskis, Executive Vice President of the European Commission for An Economy that Works for People.BERND VON JUTRCZENKA | AFP | Getty Images LONDON — The European Union will slap tariffs on up to $4 billion worth of U.S. products Monday, after what it described as a “lack of progress” on resolving a long-standing dispute over aircraft subsidies.The EU and the U.S. have been at odds over the issue since 2006. The World Trade Organization agreed last year that the EU did not follow best trade practices when granting aid to Airbus. In light of that decision, the U.S. imposed duties on $7.5 billion of imported goods from Europe.Last month, the WTO also ruled that the United States did not comply with international rules when providing subsidies to Boeing. As a result, the EU has said it is now going ahead with up to $4 billion in tariffs.- Advertisement – – Advertisement – “We have made clear at every stage that we want to settle this long-running issue. Regrettably, in spite of our best efforts, due to the lack of progress from the U.S. side, we can confirm that the European Union will later today exercise our rights and impose the countermeasures awarded to us by the WTO in respect of Boeing,” Europe’s trade chief, Valdis Dombrovskis, said on Monday during a press conference.This is a breaking news story and will be updated shortly. – Advertisement –
He led two coups, first in 1979 and then in 1981 and was an elected president from 1992 to 2001.- Advertisement –
China’s Baidu reported third-quarter revenue above market expectations on Monday and said it would buy social media platform JOYY ‘s video-based live streaming business in China for about $3.6 billion (roughly Rs. 26,800 crores).The company said through the deal it aims to diversify its revenue source, the bulk of which comes from ad sales on its core search engine platform.- Advertisement – The company said it expects current-quarter revenue to be between CNY 28.6 billion (roughly Rs. 32,400 crores) and CNY 31.3 billion (roughly Rs. 35,500 crores) compared with estimates of CNY 28.98 billion (roughly Rs. 32,900 crores).Subscribers for iQIYI touched 104.8 million in September and membership revenue rose 7 percent from a year earlier, the company said.Baidu’s Netflix-like service is in the middle of a probe by the US Securities and Exchange Commission related to accusations of inflating user numbers, revenue and the prices it pays for content by short-seller firm Wolfpack Research.- Advertisement – – Advertisement – Baidu’s vibrant mobile ecosystem enables the fast growth of its non-advertising revenue by increasing log-in users and expanding offerings like membership, live streaming and online games, Chief Executive Officer Robin Li said in a statement.The company benefited from higher paid subscribers on Baidu’s video streaming service iQIYI and a recovery in advertisement spending by businesses on its core search engine platform in the quarter.As China’s economy gradually emerges out of the COVID-19 slump, advertisement spending by businesses have also picked up from their lows during the peak of the pandemic. In September, China’s industrial output rose faster than expected and retail sales gained.- Advertisement – The company’s total revenue rose 1 percent to CNY 28.23 billion (roughly Rs. 32,000 crores) in the quarter ended September 30. Analysts on average had expected revenue of CNY 27.45 billion (roughly Rs. 31,100 crores), according to IBES data from Refinitiv.The company’s US-listed shares, which edged up initially, were down 2 percent after the bell.© Thomson Reuters 2020Will Apple Silicon Lead to Affordable MacBooks in India? We discussed this on Orbital, our weekly technology podcast, which you can subscribe to via Apple Podcasts, Google Podcasts, or RSS, download the episode, or just hit the play button below.
Pneumonic plague often starts with cough, fever, and discomfort within 2 to 6 days of infection. People develop extreme difficulty breathing as their lungs fill with fluids and can die in as little as 48 hours. CIDRAP News story on 2004 plague outbreak in Ituri regionhttp://www.cidrap.umn.edu/cidrap/content/bt/plague/news/august0204plague.html Bertherat said the outbreak can be managed. “I’m not very afraid of a risk of a big extension all over the country, because it’s a remote area,” he said, adding that “this disease is well-known and easily treatable and preventable.” Quarantine will be a challenge because the outbreak occurred in an open diamond mine with about 7,000 miners working under poor sanitary conditions, said Dr. Eric Bertherat of the WHO Alert and Response Operations program, who is leading the WHO response team. Although the epidemiologic data are incomplete, the outbreak may involve hundreds of cases, he said. “They usually die, not because of vast disseminated plague as it would be in a normal and bubonic or septicaemic form, they . . . die because of lack of oxygen,” Chu said. Providing it can enter the region, he said, the WHO team will work with local staff of the Ministry of Health and workers from the nongovernmental organizations Medecins Sans Frontieres and MedAir to ensure appropriate case management in the mine and the affected villages of Buta and Titula, as well as to trace contacts of infected people. “Right now this is a World Health Organization-led response,” Grant said. “Of course we’re on standby, but we’ve not been asked to assist.” He emphasized that absent such conditions, plague spreads less easily. It’s appropriate to be concerned about plague, but equally important not to overreact to it, he said. Antibiotics can treat the disease and prevent a secondary outbreak. Quarantine and isolation are also essential, she added. In addition, a suspected plague outbreak in the Ituri region in 2004 infected 1,042 people and killed 58, a United Nations agency reported in August 2004. Bertherat said working conditions heightened the problem. “It’s very unusual to have so many people being and working together in [such a] crowded place and in the middle of a highly endemic area for plague,” he said. The scope of their task remains hazy. Sixty-one deaths have been recorded in health facilities, he said. Many miners died as they fled the area, falling in the forest or along trails. The medical staff on the ground collected health facility data that fit the definition of pneumonic plague and found 300 to 400 suspected cases. Peters added that African mines have been implicated in other outbreaks. Gold miners in South Africa have seen pneumococcal pneumonia, which probably has the same mechanism of spread, he said. News of the Congo outbreak prompted infectious disease expert C. J. Peters, MD, to compare it with a pneumonic plague outbreak that occurred early in the twentieth century in Manchuria. Crowded, unsanitary conditions were implicated in that outbreak, said Peters, director of biodefense and professor of pathology, microbiology, and immunology at the University of Texas Medical Branch in Galveston, in a phone interview today. Llelwyn Grant, a spokesman for the Centers for Disease Control and Prevention in Atlanta, told CIDRAP News this afternoon that the CDC was aware of the reports coming out of the Congo but had not been asked to provide any support. “The living conditions were just absolutely terrible,” Peters said. People often lived in cramped underground quarters with poor ventilation. Feb 18, 2005 (CIDRAP News) – An unusual outbreak of pneumonic plague that has killed at least 61 people and potentially sickened hundreds of others is the focus of a World Health Organization (WHO) mission in a war-torn area of the Democratic Republic of the Congo (DRC). Feb 18 WHO news releasehttp://www.who.int/csr/don/2005_02_18/en/ “It’s believed that the coughs, combined with the poor ventilation and so on, led to the ready dissemination of the plague,” Peters said. The Zobia mine had been closed, but it reopened Dec 16, 2004, attracting an influx of miners from throughout the province, he said. The first case of pneumonic plague was diagnosed Dec 20, 2004. A multidisciplinary team of 10 people will leave tomorrow for the DRC, according to the transcript of a WHO news teleconference held at WHO headquarters today. The team hopes to go to the politically unstable region to support efforts to find, quarantine, and treat ill and exposed workers at the Zobia diamond mine, many of whom have fled the area. Panic, which has accompanied outbreaks of plague for hundreds of years, may foster the spread of the disease. “Maybe two-thirds of the population ran away from the mine,” traveling as far as 200 kilometers, Bertherat said. Preliminary results from rapid diagnostic tests confirmed pneumonic plague. Forty samples have been taken for culture and serology tests at the Institut de la Recherche Biomedicale in Kinshasa, WHO said. The WHO team hopes to be in the field by Tuesday, Bertherat said. Although he described existing medical treatment to date as appropriate, he also expressed a concern that local healthcare providers lack appropriate equipment. CIDRAP overview of plaguehttp://www.cidrap.umn.edu/cidrap/content/bt/plague/biofacts/index.html “Humanitarian access to this area is very difficult,” Annunziata said. “To provide any kind of epidemiological investigation or outbreak response is very problematic.” “It is difficult to be sure that really all of them are a case of pneumonic plague,” Bertherat said, and later added, “What we know is that new cases are still occurring in the mine and that yesterday, there [were] 20 cases admitted in the health facilities in Zobia, close to the mine.” See also During the Manchurian outbreak, people contracted plague either from fleas or from the marmots they killed for their pelts, he said. Once someone was ill, conditions were ripe for allowing the disease to spread. Political and economic conditions will complicate the WHO mission. The troubled Ituri region has been “most affected by very chronic and dramatic humanitarian crisis” since 1998, including armed conflict, said Dr. Giuseppe Annunziata, with the Department of Health Action in Crisis, at the teleconference. Plague is endemic in the northeastern province of Orientale, near Uganda, but this outbreak is unusual because it appears to be exclusively the pneumonic form of plague, which accounts for only 2% of reported plague cases overall, said Dr. May Chu of the WHO’s Alert and Response Operations program. The pneumonic form can spread from person to person via aerosolized bacteria, bypassing the usual route of flea bites or infective materials, she said.
Mar 6, 2007 (CIDRAP News) – A new analysis of research into the 1918 influenza pandemic, undertaken to determine whether historical accounts can illuminate planning for possible future pandemics, reveals a surprising number of enduring mysteries.In a paper published online ahead of print by the Journal of Infectious Diseases, Dr. David Morens of the National Institute of Allergy and Infectious Diseases (NAID) and Dr. Anthony Fauci, NIAID’s director, explore the relevance of the 1918 pandemic’s unanswered questions to the spread of H5N1 avian influenza as well as to novel flu viruses that may emerge in the future.Despite abundant historical accounts and almost a decade’s work on the reconstituted 1918 virus, the authors say it still is not clear where the 1918 virus originated, how it produced its unique set of symptoms, why it killed so many young people yet relatively few elderly, and whether it truly occurred in a unique pattern of short, fast-moving waves.”We must continue to examine and investigate this long-ago tragedy, allowing it to stand clearly before us as a challenge to complacency, as a modern problem with future implications, and as a grim reminder of the importance, to humanity, of continuing the fight against emerging and reemerging infectious diseases,” they write.Why the odd age distribution?The central enigma remaining from 1918 is the “extraordinary elevation in mortality in healthy young adults,” Morens said in an interview. “It’s the most insoluble problem, and also the most important, because roughly half of all the people who died were in the 20- to 40-year-old age group, and at least 50 million people died around the world.”The 1918 epidemic’s striking difference from both seasonal flu epidemics and other past pandemics, which have preyed mainly on the very young and the elderly, has never been fully explained. Researchers have hypothesized that an environmental factor—perhaps the contemporaneous invention of aspirin or the then-new social acceptance of cigarette smoking—made the young more vulnerable, or that the elderly retained some immunologic protection from a similar strain that might have circulated before those who were young in 1918 were born.”There are very few good theories and none of them really stand up,” said Morens, who has conducted historical research on 1918 in informal collaboration with Dr. Jeffrey Taubenberger, who recovered and sequenced the 1918 virus.The spike in mortality, often called the “W-shaped curve” from its appearance when graphed, has modern as well as historic resonance. A World Health Organization analysis published last month revealed that 89 percent of those sickened by H5N1 avian flu, the novel flu strain considered capable of causing a pandemic if it mutates, were younger than 40.In addition, that flu strain produces a rapid, fatal acute immune response in some of its victims—a phenomenon that to some investigators resembles the acute respiratory distress described in young victims of 1918.In a challenge to some scholarship on 1918, Morens and Fauci question how many pandemic deaths can be ascribed to that “cytokine storm” phenomenon, setting the proportion at no more than 15% and attributing the rest to secondary bacterial infections.”I think they may have underestimated the number of people who died directly from the virus,” historian John M. Barry, author of The Great Influenza: The Epic Story of the Deadliest Plague in History, said in an interview. “In certain demographic groups deaths directly attributable to the virus were higher—certainly in army camps, for instance.”Doubts about the wavesMorens and Fauci also question the long-standing interpretation that the 1918 pandemic arrived in three short, fast-moving waves that together lasted about 9 months, a sharp difference from novel flu strains’ usual pattern of reappearing annually for years.”It is dogma that there were three waves, but if you look very closely at the data, the evidence is not very strong that there were three waves anywhere but in a few countries,” Morens said.The wave phenomenon is considered critical to understanding the 1918 pandemic, because some accounts suggest that some survivors of early outbreaks acquired immunity against later, more virulent ones—an effect that modern planners would be eager to reproduce.”There was far less uniformity in the 1918 experience than people have assumed,” agreed Dr. Martin Cetron, director of the division of global migration and quarantine at the Centers for Disease Control and Prevention. He is conducting research with University of Michigan medical historian Dr. Howard Markel on how well community protective measures such as masks and quarantine worked in 1918.But Barry, whose 2004 book fired wide interest in the previously almost-forgotten pandemic, said that American and British epidemiologic analyses written not long afterward support both the occurrence of several waves and the development of immunity between one wave and the next. “There is better data than people realize,” he said.Is today’s world better prepared?Looking forward rather than backward, Morens and Fauci suggest that a modern pandemic resembling 1918 would not produce as much serious illness and death, because medical training, disease surveillance, public health infrastructure, and pharmaceuticals have improved so much since then. “The greatest burden of pandemic influenza would fall on those least privileged,” they write.But no matter how good modern medicine may be, a severe 1918-like pandemic would still trigger social havoc, said Dr. Michael Osterholm, director of the University of Minnesota’s Center for Infectious Disease Research and Policy (CIDRAP), which publishes CIDRAP News.”In terms of the developed world’s ability to respond versus the developing world’s, I think they have it almost 180 degrees backward,” he said. “Under a moderate to severe pandemic, developed-world countries that rely on a constant supply of pharmaceutical and medical products would see an interruption in trade and travel. Essential products like that will not be available.”Morens DM, Fauci AS. The 1918 influenza pandemic: insights for the 21st century. J Infect Dis 2007 Apr 1;195:1018-28 [Abstract]
Jun 6, 2008 (CIDRAP News) – The first real test of a new program to screen some arriving passengers at the Honolulu airport for flu-like illness went smoothly this week, according to an official with the Hawaii State Department of Health (DOH).The guinea pigs for the voluntary program were the passengers on a Hawaiian Airlines flight from Sydney, Australia, who were asked to fill out a questionnaire during the flight and turn it in at the airport. The purpose of the effort is to prepare for health screening that might be imposed during an influenza pandemic or other infectious disease outbreak.”The pilot [screening operation] went extremely well,” said Sarah Park, MD, deputy chief of the DOH Disease Outbreak Control Division. “I think everyone was extremely happy about how it went. It was a good demonstration of a strong collaborative process. Basically, 149 passengers were screened in about 10½ minutes.”The questionnaire responses showed there were no sick passengers on the flight, Park reported. If any had had flu-like symptoms, they would have been asked to submit to a voluntary rapid flu test requiring a throat swab.The new screening program is being funded with $289,000 from the Centers for Disease Control and Prevention (CDC). The DOH is collaborating on it with US Customs and Border Protection (CBP), the Hawaii Department of Transportation, and Hawaiian Airlines.Park said the screening is strictly voluntary. The general procedure is that passengers are given the health questionnaires while in flight and asked to complete them before landing. The forms include questions about any illness symptoms and travel history, along with demographic details. On arrival, passengers are asked to hand the questionnaires to screeners, who scan them quickly for reports of key signs and symptoms, primarily fever.Those who have symptoms are asked to submit to a rapid flu test, which takes only a couple of minutes, Park said. A person who tests positive will be given information about flu and released, assuming all signs suggest it is ordinary seasonal flu. A sample is also sent to the DOH laboratory for polymerase chain reaction testing, and the patient is later told the result.But if a passenger’s medical condition and travel history suggest the possibility of avian flu or some other serious disease, the DOH will call the CDC quarantine station at the airport, and the CDC would decide what to do from there, she said.Park said the initial goal of the program is to screen the passengers and crew of one arriving international flight per week. “As the process becomes more routine, eventually we’ll go to three flights per week and finally top off at four flights per week. It’s never been the intention to screen every international flight, but just do more of a sampling.” As of 2005, the Honolulu airport had 167 arriving international flights per week, she said.Hawaii is the first US state to launch voluntary screening for flu-like illness, the DOH said in a Jun 4 news release.”During SARS other countries screened for flu-like illness at airports,” Director of Health Chiyome Fukino, MD, said in the release. “It makes sense for the U.S. to investigate this strategy, given the very real concerns for a potential influenza pandemic. Being a global travel destination, Hawaii is a good place to start. We hope to share what we learn with the rest of the nation.”The screening program is an active surveillance effort that supplements the passive surveillance already in place for arriving international flights, Park explained. Technically, every pilot flying into the United States is required to report ahead to the airport if they are aware of a sick person on board, she said. When that happens, the CDC or an airport medical team is supposed to meet and evaluate the sick person on arrival.At the Honolulu airport, officials began testing arriving sick passengers for flu as part of the passive surveillance program in November 2005, Park said. The test is “not required, but most people agree,” she said. “There maybe have been one or two that didn’t want to do it.”In the debut of the new screening program on Jun 4, the DOH used 14 people to scan the completed questionnaires, Park reported. A key contributor to the test’s success was providing the questionnaires during the flight so people could complete them in advance. “There were no ill passengers this time, so that contributed to the efficiency of the process as well,” she said. It also helped that all the passengers spoke English.”They were all very agreeable to the process,” she said. When some passengers were asked afterward what they thought of the program, “some actually said they wondered why we didn’t ask more questions and why we didn’t ask for contact information up front. It prompted us to wonder if other travelers would be so amenable.”See also: Hawaii DOH news releaseMar 17 CIDRAP News story “CDC pandemic exercise highlights drug, mitigation, travel issues”